Mangul Lab publishes fifth paper presenting a novel method for profiling immunoglobulin (Ig) receptor repertoires from RNA-Seq

Mangul Lab at USC published a paper presenting ImReP – a novel computational tool that uses RNA-Seq data for rapid and accurate profiling of the immunoglobulin (Ig) repertoire. RNA-Seq data presents a unique opportunity to examine the adaptive immune system by profiling the both light and heavy chains that [...]

Mangul Lab joins urgent efforts to track COVID-19 by zipcode

Members of Mangul Lab have joined efforts with UCLA researchers to curate data that will help hospitals—already burdened by the COVID-19 pandemic—predict patient load in coming weeks. For the past two weeks, Jaque (Mangul Lab postdoc), Jeremy (software engineer), and Niko (undergraduate researcher) have been working with Rob Brown (UCLA [...]

By |2020-04-16T21:57:24+00:00April 8th, 2020|Categories: Lab News|Tags: , , , , , |

Mangul Lab at USC welcomes software engineer Jeremy Rotman

We are excited to welcome back a familiar face from UCLA! Jeremy Rotman recently joined Mangul Lab at USC as a software engineer. Jeremy will be constructing tools and pipelines that will help us study large, noisy biological datasets on a high performance computing cluster. Jeremy earned a Master’s degree [...]

By |2020-04-16T22:06:36+00:00March 23rd, 2020|Categories: Lab News|Tags: |

Mangul Lab submits preprint exploring read alignment techniques for short and long reads

Last week, Mangul Lab at USC shared a new preprint, which presents our group’s review of the role algorithms have on speed and efficiency of read aligners. Overview of read alignment Modern sequencing platforms generate enormous amounts of genomic data in the form of nucleotide sequences or [...]

Mangul Lab publishes first paper, a novel tool for managing bioinformatics analyses

We are proud to announce that our lab has published our first peer-reviewed paper since we established at USC School of Pharmacy in Fall 2019! Jaque, our postdoctoral scholar, is the first author on this paper! Congratulations! Our paper, which presents a novel tool for managing bioinformatics analyses on [...]

Mangul Lab submits preprint presenting a comprehensive review of the diagnostic and therapeutic potential of metagenomics

Just before the Thanksgiving holiday break, Mangul Lab at USC released our second preprint—a review of the diagnostic and therapeutic potential of metagenomics. Overview of clinical metagenomics pipeline Several members of our group—Caitlin Loeffler (Bioinformatics Analyst), Lana Martin (Project Specialist), Yutong Chang (Master’s student), Jeremy Rotman (alumni)—collaborated with [...]

Mangul Lab submits first preprint presenting app for managing high-throughput analyses via mobile device

This week, Mangul Lab at USC released our first preprint, a paper that presents Telescope - a tool developed by our group for management of cloud-based high-throughput analyses! In today’s world of big data, high-performance computational facilities are capable of processing considerable volumes of data. Computational resources capable of analyzing [...]